Column Chromatography Silica Gel

About Column Chromatography Silica Gel

Silica gel process chromatography is a high-purity, special type of silica utilized as the stationary phase in column chromatography and some other chromatographic methods. It consists of porous, granular particles with a high surface area and controlled pore size, normally 60-100 angstroms, enabling efficient separation of substances on the basis of polarity and molecular size. The size of the silica gel particle, typically between 60-120 mesh, can be chosen according to the particular demands of the separation process. The silica gel is chemically inert, thermally stable, and tolerant of a broad variety of solvents and is suitable for laboratory and industrial-scale applications such as pharmaceutical development, chemical synthesis, and natural product purification. Its stable performance and high capacity for adsorption render it a good medium to ensure accurate and efficient separations.